Hypertension, mostly essential as a clinical entity has shown its wide presence across the globe; and calcium, sodium and potassium are invariably said to have pivotal role in its causation. Although a handful of study is conducted worldwide including India, drawing their causative association with hypertension; but such a study was never conducted among population of north-east India. So, with this aim the pioneering study to verify the association of serum sodium, potassium and calcium in essential hypertensive patients as well as their first degree relatives was conducted among 180 subjects of north east India. The study vividly draws significant results statistically (p<0.001); serum sodium was high while serum calcium and potassium were low when compared with normal subjects. The study also very clearly depicts the genetic predisposition of hypertension; serum sodium was significantly high (p<0.001) among the first degree relatives of hypertensive patients, though serum potassium and calcium did not show any significant correlation. This study thus opens new avenue for the prevention as well as management of hypertension.
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